Documents for Popcorn Workers Lung

Recent Documents Related to OSHA:
* Letter from NIOSH describing safety concerns related to diacetyl substitutes
* Advance Notice of Proposed Rulemaking on diacetyl
* David Michaels's statement for OSHA's stakeholder  meeting
* OSHA's announcement of a stakeholder meeting
* Scientists’ letter to Secretary of Labor Elaine Chao
* UFCW and IBT petition (7/26/06) to Secretary Chao, and OSHA's denial of the petition (9/25/07)
* SKAPP’s letter to EPA Administrator Stephen Johnson and EPA's response
* UFCW’s petition to the National Toxicology Program
* AFL-CIO's letter to OSHA Assistant Secretary Edwin Foulke and OSHA's response
* Letter to Secretary Chao from US Representatives Miller, Owens, and Solis
* Letter from unions and scientists to Secretary of Labor Elaine Chao renewing their call for emergency action to protect workers
* 2000 letter from Missouri Department of Health to OSHA regarding a cluster of bronchiolitis obliterans cases among current and former employees at a microwave popcorn facility in Jasper, MO.
* OSHA inspector's report on the Jasper facility.
* 2001 letter to OSHA from at attorney representing sick workers from the Jasper facility.
* 2002 letter from OSHA area director explaining why no further investigation is warranted at the Jasper facility.

Recent Documents Related to Congress:
* Testimony of Eric Peoples, a former popcorn worker with bronchiolitis obliterans, at a House subcommittee hearing "Have OSHA Standards Kept up with Workplace Hazards?"
* Letter from Adam Finkel, former Director of Health Standards Programs at OSHA, to Congresswoman Woolsey in response to the House subcommittee hearing
* Legislation introduced by U.S. Representative Lynn Woolsey
* Woolsey's statement 
* Letters from OSHA Assistant Secretary Edwin Foulke, the Bush Administration, the American Bakers Association, and the industry group OSHA Fairness Coalition (also here) regarding HR 2693
* Letters from the AFL-CIO and International Brotherhood of Teamsters regarding HR 2693
* Markup of HR 2693
* Letter from George Miller, Lynn Woolsey, and Rosa DeLauro requesting that NIOSH conduct a systematic evaluation of workplace diacetyl use and related health effects.
* Letters from Senators Edward Kennedy and Patty Murray to FDA and OSHA, and FDA's response and OSHA's response
* Letter from the Department of Labor responding to the Senate Health, Education, Labor, and Pensions Committee's questions regarding OSHA's National Emphasis Program and diacetyl standard.

Recent Documents Related to FDA:
* SKAPP's petition to FDA to revoke diacetyls' GRAS status and FDA's response
* U.S. Representative Rosa DeLauro's letter requesting FDA reconsider diacetyl's GRAS status; FDA Commissioner Andrew von Eschenbach's response; and DeLauro's follow-up letter
* Letter from Cecile Rose of National Jewish Medical and Research Center to FDA

Recent Documents Related to EPA:
* EPA study on microwave popcorn emissions
* Letter from ConAgra to EPA regarding emissions from microwave popcorn bags (also see ConAgra's initial meeting request; emails regarding a meeting between ConAgra and EPA staff; and the plant confidentiality agreement)

Recent Documents Related to California:
*  Labor union petition to Cal-OSHA
* State Senator Richard Alarcon's letter to Cal-OSHA and Cal-OSHA's response
* Cal-OSHA Standards Board Response to California Labor Federation
* SKAPP's letter to Cal-OSHA on diacetyl's toxicity
* Statements from California Assemblywoman Sally Lieber for information and legislative hearings on the proposed workplace diacetyl ban
* Cal/OSHA draft standard on occupational exposure to food flavorings

Other Documents Related to Diacetyl:
* National Toxicology Program's Chemical Information Review Document for Artificial Butter Flavoring and Constituents
* Resources from the Flavor and Extract Manufacturers Association (FEMA)
* Diacetyl poster from product defense firm ChemRisk
* A news release from the IUF (International Union of Food, Agricultural, Hotel, Restaurant, Catering, Tobacco and Allied Workers' Associations) calling for government regulatory authorities around the world to take urgent action to control the use of diacetyl

Additional Documents:
Akpinar-Elci M, et al. (2004). Bronchiolitis obliterans syndrome in popcorn production plant workers. Eur Respir J 24: 298-302.

BASF (1993). Study on inhalation toxicity of diacetyl FCC as a vapor in rats: 4 hour exposure.

Boylstein R et al. (2006). Diacetyl emissions and airborne dust from butter flavorings used in microwave popcorn production. J Occup Environ Hyg 3(10): 530-535.

Centers for Disease Control and Prevention (CDC). Fixed obstructive lung disease in a microwave popcorn factory-Missouri, 2000-2002, Morbidity and Mortality Weekly Report 51: 345-347 (Apr. 26, 2002).

Centers for Disease Control and Prevention (CDC). Fixed Obstructive Lung Disease Among Workers in the Flavor-Manufacturing Industry - California, 2004-2007. Morbidity and Mortality Weekly Report 56(16);389-393 (April 27, 2007).

Council of State and Territorial Epidemiologists (CSTE) policy statement.

Fedan JS, et al. (2006). Popcorn worker's lung: In vitro exposure to diacetyl, an ingredient in microwave popcorn butter flavoring, increases reactivity to methacholine. Toxicol Appl Pharmacol 215(1): 17-22.

Harber P, et al. (2006). Diacetyl-induced lung disease. Toxicol Rev. 25(4):261-72.

Harrison R et al. Food flavoring workers with bronchiolitis obliterans following exposure to diacetyl, California, May 15, 2006.

Hendrick DJ. "Popcorn worker's lung" in Britain in a man making potato crisp flavouring. Thorax. 2008; 63: 267-268.

Horton MR. Editorial: Respiratory CSI: Diagnosing Occupationally-Related Lung Disease. Southern Medical Journal. 2008.

Hubbs AF et al. (2008). Respiratory Toxicologic Pathology of Inhaled
Diacetyl in Sprague-Dawley Rats
. Toxicol Pathol. E-pub ahead of print, doi:10.1177/0192623307312694.

Hubbs AF, et al. (2004). Necrosis of nasal and airway epithelium in rats inhaling vapors of artificial butter flavoring. Toxicol Appl Pharmacol 185: 128-135.

Kanwal R. (2008). Bronchiolitis obliterans in workers exposed to flavoring chemicals. Curr Opin Pulm Med. 14(2):141-6.

Kanwal R et al. (2006). Evaluation of flavorings-related lung disease risk at six microwave popcorn plants. J Occup Environ Med 48(2): 149-57.

Kreiss K. (2007) Occupational Bronchiolitis Obliterans Masquerading as COPD. Am J Resp Crit Care Med 176: 427-429.

Kreiss K. (2007). Flavoring-related bronchiolitis obliterans. Curr Opin Allergy Clin Immunol 7(2): 162-7.

Kreiss K, et al. (2002). Clinical bronchiolitis obliterans in workers at a microwave-popcorn plant. N Engl J Med 347(5): 330-338.

Kullman G et al. (2005). Characterization of respiratory exposures at a microwave popcorn plant with cases of bronchiolitis obliterans. J Occup Environ Hyg 2: 169-78.

Materna B. (2007). Summary of eight known cases of confirmed or obstructive lung disease in California food flavor manufacturing workers.

Modi P, et al (2008).A Case of Flavor-Induced Lung Disease. Southern Medical Journal. 101(5): 541-542.

Morgan DL, Flake GP, Kirby PJ, Palmer SM. (2008). Respiratory toxicity of diacetyl in C57BL/6 mice. Toxicol Sci. 2008 Jan 27; [Epub ahead of print].

National Institute for Occupational Safety and Health (NIOSH) alert: "Preventing lung disease in those who use or make flavorings." (2004).

NIOSH. Health Hazard Evaluation Report. HETA-85-171-1710: International Bakers Services, Inc., South Bend, Indiana. (July 1986).

NIOSH. Health Hazard Evaluation Report. HETA 2003-0112-2949: ConAgra Snack Foods, Marion, Ohio. (December 2004).

NIOSH. Health Hazard Evaluation Report. HETA-2000-0401-2991: Gilster-Mary Lee Corporation, Jasper, Missouri. (January 2006).

NIOSH. Health Hazard Evaluation Report. HETA 2006-0303-3043: Carmi Flavor and Fragrance Company, Inc., Commerce, California. (April 2007).

NIOSH. Letter to Frank Morrison, Nebraska Popcorn, regarding HETA 2002-0089: Nebraska Popcorn, Clearwater, Nebraska. (July 2, 2003.)

NIOSH. Letter to Keith Heuermann, B.K. Heuermann Popcorn, regarding HETA 2001-0517: B.K. Heuermann Popcorn Inc., Phillips, Nebraska. (May 13, 2003).

NIOSH. Heath Hazard Evaluation Report. HETA 2001-0474-2943: American Pop Corn Company. (July 2004).

NIOSH. Health Hazard Evaluation Report. HETA-2002-0408-2915: Agrilink Foods Popcorn Plant, Ridgeway, Illinois. (October 2003).

NIOSH. Health Hazard Evaluation Report. HETA-206-0195-3044: Yatsko's Popcorn, Sand Coulee, Montana. (April 2007).

NIOSH. Health Hazard Evaluation Interim Report. HETA-2007-0033: Gold Coast Ingredients, Inc., Commerce, California. (March 2007).

NIOSH. Health Hazard Evaluation Interim Report 2. HETA-2007-0033: Gold Coast Ingredients, Inc., Commerce, California. (August 2007).

Olmedo M. Letter from director, OSHA Regional Office (Kansas City, MO), regarding complaint against Gilster Mary Lee Corporation. (February 28, 2002).

Parmet AJ, Von Essen S. (2002). Rapidly progressive, fixed airway obstructive disease in popcorn workers: a new occupational pulmonary illness? J Occup Environ Med 44: 216-218.

Pendergrass SM. (2004). Method development for the determination of diacetyl and acetoin at a microwave popcorn plant. Environ Sci Technol 38(3): 858-61.

Rosati JA, Krebs KA, and Liu X. (2007). Emissions from Cooking Microwave Popcorn. Critical Reviews in Food Science and Nutrition. 47:8, 701 - 709.

Schachter EN. (2002). Popcorn workers lung. N Engl J Med 347(5): 360-61.

Schneider A. Disease is swift, response is slow.  Baltimore Sun. (April 23, 2006).

Van Rooy F et al. Bronchiolitis Obliterans Syndrome in Chemical Workers Producing Diacetyl for Food Flavorings. Am J Resp Crit Care Med 176: 498-504.